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Improving Safety and Accuracy of Stereotactic Brain Biopsies in Primary Central Nervous System Lymphoma.

NCT06263361 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2025-06-11

No results posted yet for this study

Summary

Primary central nervous system lymphoma (PCNSL) is an aggressive extranodal non- Hodgkin lymphoma exclusively localized into the nervous system. The aim of this study is to evaluate the MRI imaging characteristics of the peritumoral area (PTA) and to correlate this information to pathological findings.

Conditions

  • Cerebral Lymphoma

Interventions

DIAGNOSTIC_TEST

MRI imaging

To characterize the peritumoral area in PCNLs through the use of advanced MRI sequences.

DIAGNOSTIC_TEST

Cerebral biopsy

To evaluate the predictive value of sodium fluorescence to confirm ex-vivo the diagnostic tumor tissue prior to histopathological examination.

Sponsors & Collaborators

  • IRCCS San Raffaele

    lead OTHER

Principal Investigators

  • Pietro Mortini, MD, Prof. · IRCCS San Raffaele Scientific Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-01
Primary Completion
2028-12-31
Completion
2029-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06263361 on ClinicalTrials.gov