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Tranexamic Acid Instillation in Laparoscopic Cholecystectomy

NCT06246422 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 91

Last updated 2025-02-24

No results posted yet for this study

Summary

Adult patients undergoing laparoscopic cholecystectomy are at high risk to develop postoperative bleeding especially in the presence of severe adhesions. Local instillation of the antifibrinolytic (tranexamic acid) at the gall bladder bed may decrease the risk of bleeding.

The aim of this study is to evaluate the role of topical administration of Tranexamic acid on gallbladder bed for prophylaxis against bleeding in cases of difficult dissection cases due to acute inflammation and dense adhesions.

Conditions

  • Postoperative Complications

Interventions

DRUG

Tranexamic Acid 500 MG

Local instillation of 500 mg tranexamic acid in 20 ml normal saline in the gall bladder bed

DRUG

Normal saline

Local instillation of 20 ml normal saline in the gall bladder bed

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-11
Primary Completion
2022-12-13
Completion
2022-12-13

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06246422 on ClinicalTrials.gov