A Trial to Evaluate the Safety and Preliminary Efficacy of iNK in the Treatment of Subjects With Solid Tumor
NCT06245018 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2024-02-07
Summary
This trial is to investigate the safety, efficacy of iNK in subjects with solid tumor. It is a dose escalation and extension trial.
Conditions
Interventions
- BIOLOGICAL
-
iNK Injection
Subjects will receive about 4 cycles of iNK
Sponsors & Collaborators
-
Nuwacell Biotechnologies Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2027-03-01
- Completion
- 2030-03-01
More Related Trials
-
A Study of GC203 TIL in Advanced Malignant Solid Tumors
NCT06375187 ·Status: RECRUITING ·Phase: PHASE1
-
Vaccine Therapy Plus QS21 in Treating Patients With Small Cell Lung Cancer That Has Responded to Initial Therapy
NCT00004249 ·Status: COMPLETED ·Phase: PHASE2
-
Tumor Cell Vaccine in Treating Patients With Advanced Cancer
NCT00002505 ·Status: COMPLETED ·Phase: PHASE2
-
Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma
NCT07144384 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Cytokine-induced Killer Study for Patients With Stage II Melanoma
NCT02498756 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
One Trial of JCXH-211 Intratumoral Injection Combined With Anti-PD-1 Antibody in Patients With Malignant Solid Tumors
NCT06781125 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma Patients
NCT06730009 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors
NCT06546150 ·Status: RECRUITING ·Phase: PHASE1
-
Clinical Trial of Infusion of Activated NK Cells for the Treatment of Sarcomas
NCT05952310 ·Status: RECRUITING ·Phase: NA
-
The IIT Study of Evaluation of P-IL-2 Single Agent and With Anti-PD-1
NCT05829057 ·Status: RECRUITING ·Phase: PHASE1
-
Interleukin-7 in Treating Patients With Refractory Solid Tumors
NCT00062049 ·Status: COMPLETED ·Phase: PHASE1
-
Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer
NCT00674258 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
NCT00098917 ·Status: TERMINATED ·Phase: PHASE1
-
Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia
NCT05987696 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00019929 ·Status: COMPLETED ·Phase: PHASE2
-
An Immunogenic Personal Neoantigen Vaccine for Cancer Treatment
NCT04087252 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of OVV-01 Injection in Combination With IBR900 Cell Injection in Patients With Advanced Malignant Tumors
NCT05271279 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma
NCT04309084 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of TIL in Advanced Solid Tumors (DFGD)
NCT06488950 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
ImmuniCell® in Patients With Advanced Cancers
NCT02459067 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
NCT06566092 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors
NCT00002994 ·Status: COMPLETED ·Phase: PHASE1
-
The Adoptive Immunotherapy for Solid Tumors Using Modified Autologous CIK Cells
NCT01868490 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1/PHASE2
-
Peptide Vaccine Targeting to Cancer Specific Antigen Combined With Anti-angiogenic Peptide Antigen in Treating Patients With Non-small Cell Lung Cancer
NCT00874588 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Systemic Allogenic NK Cells in R/R Neuroblastoma
NCT06674265 ·Status: RECRUITING ·Phase: PHASE1