Tumor Cell Vaccine in Treating Patients With Advanced Cancer
NCT00002505 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2011-05-12
Summary
RATIONALE: Vaccines made from the patient's cancer cells may make the body build an immune response and kill their tumor cells.
PURPOSE: Randomized phase II trial to study the effectiveness of autologous tumor cell vaccination plus immunologic adjuvant in treating patients who have metastatic cancer.
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- BIOLOGICAL
- BIOLOGICAL
-
recombinant interferon gamma
- BIOLOGICAL
-
tumor cell lysate vaccine therapy
Sponsors & Collaborators
-
Cancer Biotherapy Research Group
collaborator OTHER -
Hoag Memorial Hospital Presbyterian
lead OTHER
Principal Investigators
-
Robert O. Dillman, MD, FACP · Cancer Biotherapy Research Group
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1992-08-31
- Primary Completion
- 2002-08-31
- Completion
- 2006-05-31
Countries
- United States
Study Locations
More Related Trials
-
Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer
NCT00002475 ·Status: COMPLETED ·Phase: PHASE2
-
Non-Viral TCR Gene Therapy
NCT04102436 ·Status: WITHDRAWN ·Phase: PHASE2
-
Trial of G250 Peptide and IL-2 Following Surgical Resection of Locally Advanced/Metastatic Renal Cell Carcinoma
NCT00203866 ·Status: TERMINATED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Cancer
NCT00021164 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer
NCT00027534 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019448 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Therapy in Treating Patients With Metastatic Melanoma
NCT00045357 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer
NCT00028496 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy Plus Sargramostim in Treating Patients With Stage III or Stage IV Cancer
NCT00005023 ·Status: COMPLETED ·Phase: PHASE1
-
Interleukin-2 Plus Activated White Blood Cells in Treating Patients With Cancer That Has Not Responded to Chemotherapy or Radiation Therapy
NCT00019357 ·Status: COMPLETED ·Phase: PHASE1
-
Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer
NCT00002504 ·Status: COMPLETED ·Phase: PHASE2
-
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
NCT03412877 ·Status: RECRUITING ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00017355 ·Status: UNKNOWN ·Phase: PHASE1
-
Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor
NCT00069940 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00054535 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer
NCT00052351 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotherapy in Treating Patients With Metastatic Breast Cancer
NCT00003432 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Treatment for Advanced Breast Cancer
NCT00090480 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy and Sargramostim in Treating Patients With Non-small Cell Lung Cancer
NCT00005630 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma
NCT01026051 ·Status: TERMINATED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer
NCT00017537 ·Status: WITHDRAWN ·Phase: PHASE1
-
Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer
NCT00048893 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer
NCT00814892 ·Status: TERMINATED ·Phase: PHASE2
-
HER-2/Neu Vaccine Plus GM-CSF in Treating Patients With Stage III or Stage IV Breast, Ovarian, or Non-small Cell Lung Cancer
NCT00003002 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With or Without Sargramostim in Treating Patients With Cancer
NCT00009958 ·Status: TERMINATED ·Phase: PHASE1