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Speech Pattern Evaluation and Analysis for Knowledge of AD

NCT06230783 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 165

Last updated 2026-03-12

No results posted yet for this study

Summary

The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease.

Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years.

Conditions

  • Wisconsin Alzheimer's Disease Research Center
  • Wisconsin Registry for Alzheimer's Prevention

Interventions

OTHER

TalkTracker

Participants will be asked to complete the speech collection procedures remotely/at home once per week for 8 weeks. The 8-week period of weekly remote speech collection will take place yearly for a total of 3 years. At the end of each 8-week study period for years 1-3, participants will complete a survey that asks questions about how easy/difficult the application was to use, how frustrated they felt using the application, and other usability questions.

Sponsors & Collaborators

  • Arizona State University

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • Kimberly D Mueller, PhD, CCC-SLP · University of Wisconsin, Madison

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-22
Primary Completion
2029-02-28
Completion
2029-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06230783 on ClinicalTrials.gov