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Electro-clinical Features and Functional Connectivity Analysis in SYN1 Gene Mutation-related Epilepsy

NCT06222840 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2024-01-25

No results posted yet for this study

Summary

SYN1 gene mutation is an X-linked gene mutation that causes numerous pathological manifestations such as seizures and neurodevelopmental disorders. A few descriptions of this disease have been published in the last decade, but the electro-clinical features of epilepsy are still largely unknown. No analysis of electroencephalographic connectivity has yet been performed. The aim of this study is to perform a detailed electro-clinical seizure analysis and electroencephalographic analysis in patients with a SYN1 gene mutation, in an attempt to identify a characteristic pattern that would allow earlier diagnosis and better understanding and management of this disease.

Conditions

  • Epileptic Syndromes

Interventions

OTHER

Electro-clinical analysis of epileptic seizures

Electro-clinical analysis of epileptic seizures

OTHER

Electro-encephalographic cases

Electro-encephalographic connectivity analysis compared to controls

OTHER

Clinical datas analysis

Clinical datas analysis

OTHER

Electro-encephalographic control

Electro-encephalographic connectivity analysis compared to cases

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Saint Etienne

    lead OTHER

Principal Investigators

  • Laure MAZZOLA, MD · CHU SAINT-ETIENNE

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2023-10-31
Completion
2023-10-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06222840 on ClinicalTrials.gov