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Assessing the Impact of Opioid-Free Anesthesia Using the Modified Mulimix Technique.

NCT06216210 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2024-01-22

No results posted yet for this study

Summary

The effective management of post-operative pain in the setting of bariatric surgery presents significant hurdles for both anesthesiologists and surgeons. The objective of this study was to assess the effects of opioid-free anesthesia (OFA) using the modified mulimix technique on the levels of plasma interleukin-2 (IL-2) and interleukin-6 (IL-6) as the primary outcome. Additionally, the study aimed to evaluate the duration of analgesia and the analgesic requirements within the first twenty-four hours after surgery.

Conditions

  • Opioid Use

Interventions

DRUG

opioid-FREE anesthesia.

They received opioid-free anesthesia. These patients were provided a multimodal combination infusion. The administration of this infusion commenced at a dosage of 0.2 micrograms per kilogram per hour of dexmedetomidine. The "Modified Mulimix" cocktail, consisting of dexmedetomidine at a concentration of 10 ug/ml, Ketamine at a concentration of 2.5 mg/ml, and Lignocaine at a concentration of 20 mg/ml, was administered to a patient weighing 100 kg and if the weight is 110 Kg the rate will be increased by 10 percent, etc.,

DRUG

opioid-CONTAINING anesthesia.

The process of inducing anesthesia included the injection of fentanyl at a dosage of 2 micrograms per kilogram during the induction phase. Additionally, morphine was administered at a dose of 0.03 milligrams per kilogram at the time of port insertion.

Sponsors & Collaborators

  • Zulekha Hospitals

    lead OTHER

Principal Investigators

  • SAMEH HA SEYAM, MD · assistant professor of anesthesiology, intensive care, and pain management, A-Azhar university

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-04-22
Primary Completion
2023-10-04
Completion
2023-10-04

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06216210 on ClinicalTrials.gov