Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study
NCT06208202 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2026-03-23
Summary
This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.
Conditions
- Abuse Tobacco
- Exposure
Interventions
- BEHAVIORAL
-
Behavioral Intervention
Receive and use flavored e-cigarettes (EC) as directed
- OTHER
-
Biospecimen Collection
Undergo biosample sample collection
- OTHER
-
Survey Administration
Complete surveys
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Ohio State University Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Alayna P Tackett, PhD · Ohio State University Comprehensive Cancer Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 21 Years
- Max Age
- 29 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-05-08
- Primary Completion
- 2027-12-31
- Completion
- 2028-06-30
Countries
- United States
Study Locations
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