Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study

NCT06208202 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2026-03-23

No results posted yet for this study

Summary

This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.

Conditions

  • Abuse Tobacco
  • Exposure

Interventions

BEHAVIORAL

Behavioral Intervention

Receive and use flavored e-cigarettes (EC) as directed

OTHER

Biospecimen Collection

Undergo biosample sample collection

OTHER

Survey Administration

Complete surveys

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH
  • Ohio State University Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Alayna P Tackett, PhD · Ohio State University Comprehensive Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
29 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-08
Primary Completion
2027-12-31
Completion
2028-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06208202 on ClinicalTrials.gov