MedTrace Logo

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography

NCT06200519 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 216

Last updated 2026-03-04

No results posted yet for this study

Summary

The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined antenatal, intrapartum, maternal, and neonatal factors on cardiac function.

The main question it aims to answer are:

* What are the normal reference ranges for parameters of diastolic cardiac function in neonates?
* How are these influenced by maternal, intrapartum and neonatal factors?
* Do the diastolic changes noted during the first two days of life persist into infancy?

Participants will have four echocardiographic assessments in total:

* Two during the first 48 hours of life (prior to discharge home)
* Two during infancy (as an outpatient)

Conditions

  • Diastolic Dysfunction
  • Neonatal Encephalopathy
  • Small for Gestational Age at Delivery
  • Transient Tachypnea of the Newborn
  • Trisomy 21
  • Gestational Diabetes

Sponsors & Collaborators

  • University College Cork

    lead OTHER

Principal Investigators

  • Eugene Dempsey · University College Cork

Eligibility

Min Age
6 Hours
Max Age
18 Hours
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-12
Primary Completion
2026-05-31
Completion
2026-07-31

Countries

  • Ireland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06200519 on ClinicalTrials.gov