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Design of Personalised SupplemenTs Based on the Gut MicRobiota Through Artificial Intelligence for Alzheimer's Patients

NCT06199193 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2024-12-09

No results posted yet for this study

Summary

Studies indicate that the intestinal microbiota could have an implication in Alzheimer's disease; recently, a positive relationship has been established between levels of bacterial lipopolysaccharide (LPS) and cerebral amyloidosis and a negative relationship between the production of the chain fatty acid cuts butyrate by the intestinal microbiota and cerebral amyloidosis. Currently there is no effective treatment for Alzheimer's, but studies indicate that a healthy diet such as the Mediterranean diet and physical exercise delay the symptoms of this disease. For all these reasons, it is postulated that introducing changes in the intestinal microbiota through diet may be a new treatment or serve as an adjuvant treatment for Alzheimer's disease.

Conditions

  • Alzheimer Disease
  • Gut Microbiota

Interventions

DIETARY_SUPPLEMENT

Personalized diet

Personalized supplement designed by artificial intelligence based on the intestinal microbiota and incorporated into diets

DIETARY_SUPPLEMENT

Dietary counseling

Dietary advice will be provided to adapt the diet to the nutritional objectives and recommended intakes.

Sponsors & Collaborators

  • Hospital Universitario Virgen de la Arrixaca

    collaborator OTHER

  • Universidad Europea de Madrid

    collaborator OTHER

  • Puerta de Hierro University Hospital

    collaborator OTHER

  • Universidad Complutense de Madrid

    lead OTHER

Principal Investigators

  • Mar Larrosa, PhD · Universidad Complutense de Madrid

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-01
Primary Completion
2025-04-01
Completion
2025-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06199193 on ClinicalTrials.gov