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Myocardial Stiffness Evaluation in Patients With Heart Failure With Preserved Ejection Fraction

NCT06196086 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 438

Last updated 2024-01-09

No results posted yet for this study

Summary

The goal of this observational study is to evaluating myocardial stiffness in patients with heart failure with preserved ejection fraction (HFpEF) by intrinsic wave velocity propagation (IVP). The main questions it aims to answer are:

* Whether myocardial stiffness assessed by IVP in patients with HFpEF Increased.
* Whether IVP is related to the cardiac structure and function in patients with HFpEF.
* What are the risk factors that may be associated with heart failure rehospitalization in patients with HFpEF?
* Whether increased myocardial stiffness is a risk factor for heart failure rehospitalization.

Participants will undergo transthoracic echocardiography to obtain conventional ultrasound parameters, and software post-processing analysis to obtained two-dimensional strain parameters and IVP, as well as general clinical data and laboratory test results. Clinical followed up was performed through electronic medical records or telephone interviews until patient rehospitalization for heart failure or discharge for one year.

Conditions

Interventions

DIAGNOSTIC_TEST

Echocardiography examination

Echocardiography examination and software post-processing analysis was performed to obtain parameters of conventional echocardiography, left atrial and left ventricle strain, and IVP.

Sponsors & Collaborators

  • Haiyan Wang

    lead OTHER

Principal Investigators

  • Haiyan Wang · Shandong First Medical University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-12-20
Primary Completion
2026-12-20
Completion
2027-12-20

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06196086 on ClinicalTrials.gov