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Greater-Bay-Area Healthy Aging Brain Study (GHABS)

NCT06183658 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1400

Last updated 2025-05-14

No results posted yet for this study

Summary

The goal of this observational study is to learn about the pathophysiology characterization and evolutionary patterns of Alzheimer's disease (AD) in South China older adults. The primary purposes are as follows:

1. The prevalence and characteristics of AD in South China's aging population
2. Identify novel biomarkers and neuroimaging techniques for early detection and intervention of AD
3. Supporting and fertilizing novel approaches and techniques for early diagnosis and intervention of AD Participants will undergo cognitive assessments, blood sample collection, and genetic testing. Some will undergo CSF collection, stool sample collection, MRI scanning, Aβ PET scanning, and tau PET scanning.

Conditions

Interventions

DIAGNOSTIC_TEST

Fluids biomarker and neuroimaging of AD diagnosis

Early diagnosis of Alzheimer's disease in South China aging population using fluids biomarker and neuroimaging.

Sponsors & Collaborators

  • National Natural Science Foundation of China

    collaborator OTHER_GOV

  • Guangdong Basic and Applied Basic Science Foundation

    collaborator UNKNOWN

  • Shenzhen Science and Technology Innovation Commission

    collaborator UNKNOWN

  • Shenzhen Bay Laboratory

    lead OTHER

Principal Investigators

  • Tengfei Guo, Ph.D. · Shenzhen Bay Laboratory

Eligibility

Min Age
55 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2026-04-30
Completion
2026-04-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06183658 on ClinicalTrials.gov