Investigation on the Efficacy of Oral Carnitine Challenge Test Based on a Gut Microbiota Functional Test
NCT06175260 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 91
Last updated 2023-12-18
Summary
This study seeks to enlist healthy volunteers to form a validation cohort. The purpose is to confirm the observed correlations between the gut microbiome and the capacity to produce trimethylamine N-oxide (TMAO), which will be assessed using the oral carnitine challenge test (OCCT).
Conditions
- Dysbiosis
- Healthy
Interventions
- DIAGNOSTIC_TEST
-
oral carnitine challenge test
Urine samples will be collected to quantify trimethylamine N-oxide (TMAO) levels at four time points: before, and 24, 48, and 72 hours after the oral administration of 1500 mg of L-carnitine.
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Ming-Shiang Wu, MD, PhD · National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-06-05
- Primary Completion
- 2021-05-14
- Completion
- 2022-06-30
Countries
- Taiwan
Study Locations
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