Influence of Intermittent Fasting on Locally Advanced Breast Cancer Patients
NCT06174259 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66
Last updated 2024-02-01
Summary
Breast cancer is the most common cancer type among women in Egypt and world. Preclinical studies show fasting reduces growth factors and modulates nutrient sensing systems, protecting normal cells against chemotherapy. However, cancer cells are not protected due to Differential Stress Resistance (DSR), making them more vulnerable to chemotherapeutics. This study aims to evaluate intermittent fasting impact on neoadjuvant chemotherapy in breast cancer patients.
Conditions
- Locally Advanced Breast Cancer
- Intermittent Fasting
Interventions
- OTHER
-
intermittent fasting
16/8 intermittent fasting (limiting foods and calorie-containing beverages to a set window of 8 hours per day)
Sponsors & Collaborators
-
Menoufia University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-06-01
- Primary Completion
- 2024-06-01
- Completion
- 2025-06-01
Countries
- Egypt
Study Locations
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