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Microbiome in the Acute Stage of New Onset Paediatric Type 1 Diabetes

NCT06157736 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2024-05-30

No results posted yet for this study

Summary

The goal of this observational study is to learn more about the microbiome and metabolome of children with type 1 diabetes (T1D). The main questions it aims to answer are:

1. Do the microbiome and metabolome play a role in the onset and presentation of T1D?
2. How do the microbiome and metabolome evolve during the early stages of T1D?
3. Are there are differences in the microbiome or metabolome of children who present with diabetic ketoacidosis (DKA) versus those who present without DKA, and between those who present with mild, moderate or severe DKA?
4. Is there an association between the microbiome or metabolome and glycaemic control during the first year of diagnosis?
5. Is there an association between the microbiome or metabolome and beta cell reserve after one year of T1D disease?

Conditions

Sponsors & Collaborators

  • APC Microbiome Ireland

    collaborator UNKNOWN

  • University College Cork

    lead OTHER

Principal Investigators

  • Colin Hawkes · University College Cork

Eligibility

Min Age
6 Months
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-06
Primary Completion
2025-08-31
Completion
2025-08-31

Countries

  • Ireland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06157736 on ClinicalTrials.gov