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Regression of Cervical Precancerous Lesions and Associated Risk Factors

NCT06147388 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-02-25

No results posted yet for this study

Summary

The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.

Conditions

  • Cervix Uteri SIL
  • HPV
  • CIN2
  • CIN3

Interventions

DIAGNOSTIC_TEST

Colposcopy

No surgery, observation

Sponsors & Collaborators

  • General University Hospital, Prague

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-01
Primary Completion
2026-07-01
Completion
2027-07-01

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06147388 on ClinicalTrials.gov