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THE EFFECT OF VITAMIN C ON POST-ORTHODONTIC TREATMENT RELAPSE

NCT06146296 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-11-24

No results posted yet for this study

Summary

The aim of this study is to evaluate and compare the effect of locally injected and orally administered (systemic) Vitamin C on post-orthodontic treatment relapse

Conditions

  • Orthodontic Relapse

Interventions

BIOLOGICAL

Local Vitamin C injection

An injection of 1-1.5 ml of L-ascorbic acid, locally introduced in relation to the keratinized gingival tissues, with extension to the whole target region successively. The injected area will be massaged for equal distribution of the injected vitamin. Injections will be performed on the first day of retainer delivery (T0), after 1 month (T1), after 3 months (T2), and after 6 months (T3). Hence, a total of 4 local Vit-C injections will be performed over the study period.

BIOLOGICAL

Oral Vitamin C supplement

Patients will be prescribed a daily oral (systemic) Vit-C supplement to be taken over the follow up period.

Sponsors & Collaborators

  • Nourhan M.Aly

    lead OTHER

Principal Investigators

  • Samar M Adel, PhD · Alexandria University

  • Farah Y Eid, PhD · Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-01
Primary Completion
2024-06-01
Completion
2024-06-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06146296 on ClinicalTrials.gov