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Population Pharmacokinetics of Paracetamol in Overweight and Obese Children

NCT06135389 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-01-20

No results posted yet for this study

Summary

The main objective of the study is to define population pharmacokinetic parameters and variability factors for paracetamol and its metabolites in overweight and obese children compared to children with normal weight for age and sex.

Conditions

Interventions

BIOLOGICAL

Titration of paracetamol and its metabolites - scheme1

15 to 20 minutes and 1 to 2 hours after first perfusion and before second perfusion/administration of paracetamol

BIOLOGICAL

Titration of paracetamol and its metabolites - scheme 2

30 to 40' after first perfusion and before second perfusion/administration of paracetamol (residual concentration)

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Sihem BENABOUD, MD, PhD · Assistance Publique - Hôpitaux de Paris

Eligibility

Min Age
6 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-31
Primary Completion
2026-03-31
Completion
2026-03-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06135389 on ClinicalTrials.gov