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Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy

NCT06125340 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2024-12-12

No results posted yet for this study

Summary

Children are commonly hospitalized because of community-acquired pneumonia (CAP). There are multiple high-quality randomized trials of short-course antibiotic therapy (3-5 days of treatment) for adults hospitalized with CAP - but there is very little evidence in children. We intend to do a pilot RCT of short-course (3-5 days) vs standard-duration (8-10 days) antibiotic therapy for children hospitalized for CAP.

Conditions

  • Community-acquired Pneumonia

Interventions

DRUG

Placebo

5 days of placebo to be given after 3-5 days of antibiotics

DRUG

Amoxicillin

Standard-dose amoxicillin (approved by Health Canada) to be given x 5 days.

Sponsors & Collaborators

  • Jeffrey

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
6 Months
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-17
Primary Completion
2025-11-30
Completion
2026-01-01

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06125340 on ClinicalTrials.gov