Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke
NCT06120725 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 580
Last updated 2023-12-29
Summary
Along with the current clinical trial, the efficacy and safety of 180 mg loading dose of ticagrelor administered within 24 hours of first-ever large-vessel ischemic stroke compared to 300 mg clopidogrel were assessed through NIHSS, mRS, and possible adverse effects.
Conditions
Interventions
- DRUG
-
Ticagrelor 90 MG
Efficacy and safety of 180 mg loading dose of ticagrelor administered within 24 hours of first-ever ischemic stroke followed by 90 mg bid for 3 months will be assessed through NIHSS, mRS, duration of hospital stay, new ischemic stroke, and possible adverse effects.
- DRUG
-
Clopidogrel
Efficacy and safety of 300 mg clopidogrel followed by 75 mg once daily for 3 months will be assessed through NIHSS, mRS, duration of hospital stay, new ischemic stroke, and possible adverse effects.
Sponsors & Collaborators
-
Kafrelsheikh University
lead OTHER
Principal Investigators
-
mohamed G. Zeinhom, MD · neurology department kafr el-sheikh university
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-09-01
- Primary Completion
- 2023-09-01
- Completion
- 2023-11-01
- FDA Drug
- Yes
Countries
- Egypt
Study Locations
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