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RESISTance Exercise for Depression Trial

NCT06110897 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2026-05-05

No results posted yet for this study

Summary

Depression is a leading cause of disability worldwide and current treatments are ineffective for many people. This trial will investigate the efficacy of a 16-week high vs low dose resistance exercise training program for the treatment of Major Depressive Disorder (MDD) in 200 adults.

Conditions

Interventions

BEHAVIORAL

High Dose Resistance Exercise Training

Progressive resistance exercise training

BEHAVIORAL

Low Dose Resistance Exercise Training Group

Progressive resistance exercise training

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Iowa State University

    collaborator OTHER

  • University of Minnesota

    collaborator OTHER

  • University of Limerick

    collaborator OTHER

  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • Jacob Meyer, PhD · University of Wisconsin, Madison

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-01
Primary Completion
2028-11-01
Completion
2029-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06110897 on ClinicalTrials.gov