Impact of an Eight Week Exercise Intervention in Treating Major Depressive Disorder
NCT03191994 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2017-06-20
Summary
To investigate the impact of a structured eight week exercise intervention as an add-on therapy in treating Major Depressive Disorder. Using behavioural techniques and neuroimaging to measure changes in brain function following an exercise intervention in people with clinical depression. By correlating changes in the hippocampus with changes in HPA axis hormones, inflammatory cytokines and growth factors it is possible to determine which of the biochemical markers is most predictive of improved neural function.
Conditions
Interventions
- BEHAVIORAL
-
Exercise
a structured, supervised eight week moderate intensity exercise intervention
Sponsors & Collaborators
-
University of Ontario Institute of Technology
lead OTHER
Principal Investigators
-
Bernadette Murphy, PhD · University of Ontario Institute of Technology
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-01-02
- Primary Completion
- 2017-12-31
- Completion
- 2018-06-30
Countries
- Canada
Study Locations
More Related Trials
-
Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients.
NCT02741622 ·Status: COMPLETED ·Phase: NA
-
Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders
NCT06450704 ·Status: RECRUITING ·Phase: NA
-
Cognitive Training for Depression
NCT01936506 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Neurocognitive Enhancement in Major Depressive Disorder
NCT00998569 ·Status: COMPLETED ·Phase: NA
-
Feasibility of Resistance Exercise to Treat Major Depression Via Cerebrovascular Mechanisms
NCT05695365 ·Status: COMPLETED ·Phase: NA
-
Acute Aerobic Exercise and Neuroplasticity in Depression
NCT02839837 ·Status: COMPLETED ·Phase: NA
-
RESISTance Exercise for Depression Trial
NCT06110897 ·Status: RECRUITING ·Phase: NA
-
Imagery Rescripting as Treatment for Depression
NCT05976945 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Exercise Recovery From Persistent Depression: A Thematic Analysis
NCT05539495 ·Status: COMPLETED
-
fMRI Study of Treatment Changes in Major Depression
NCT01027559 ·Status: COMPLETED ·Phase: NA
-
Therapeutic Effectiveness of Exercise Associated to the Pharmacotherapy in Major Depression
NCT02427789 ·Status: COMPLETED ·Phase: NA
-
Trial Investigating the Effect of Different Exercise Forms on Depression
NCT00103415 ·Status: UNKNOWN ·Phase: NA
-
Movement for Depression - An RCT Assessing the Effects of Physical Activity Promotion for People With MDD
NCT03403881 ·Status: UNKNOWN ·Phase: NA
-
Organizational Strategies and Psychosocial Skills for Maintaining Physical Activity After a Depressive Episode: a 3-month Post-rehabilitation Study.
NCT07129928 ·Status: NOT_YET_RECRUITING
-
Testing the Effectiveness of a Computer-based Program for Depression
NCT01203683 ·Status: COMPLETED ·Phase: PHASE3
-
Improving Depressive Symptoms Through Personalised Exercise and Activation
NCT04857944 ·Status: COMPLETED ·Phase: NA
-
The Effects of Exercise on Gut Bacteria, Mood and Cognition in Depression
NCT06398496 ·Status: RECRUITING ·Phase: NA
-
Depression, Experiential Diversity, and Behavioral Novelty
NCT05767554 ·Status: COMPLETED ·Phase: NA
-
Fitness for Brain Optimization for Late-Life Depression
NCT04670510 ·Status: COMPLETED ·Phase: NA
-
Using Neuroimaging to Investigate Major Depressive Disorder
NCT00781677 ·Status: COMPLETED
-
Sexual Health on Antidepressants Through Physical Exercise
NCT01188720 ·Status: COMPLETED ·Phase: NA
-
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
NCT05703685 ·Status: RECRUITING ·Phase: PHASE1
-
Functional and Metabolic Changes in the Course of Antidepressive Treatment
NCT02099630 ·Status: COMPLETED
-
Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study
NCT07247344 ·Status: RECRUITING
-
MRI Studies of Emotion in Depression
NCT02429011 ·Status: COMPLETED