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Respiratory Muscle Assesment in COVID-patients Without Hospitalization

NCT06105450 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2026-01-28

No results posted yet for this study

Summary

Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory physiology laboratory in patients who were not hospitalized during the acute COVID-19-infection but still complain of different persistent symptoms including exertional dyspnea and fatigue.

Conditions

  • Covid19
  • Diaphragm Injury

Interventions

DIAGNOSTIC_TEST

Comprehensive assessment of respiratory muscle function.

Comprehensive assessment of respiratory muscle function to the point of its invasive assessment with recordings of twitch transdiaphragmatic pressure in response to magnetic phrenic nerve stimulation and stimulation of the lower thoracic nerve roots.

Sponsors & Collaborators

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Michael Dreher, Professor · RWTH Aachen University

  • Jens Spiesshoefer, MD · RWTH Aachen University

  • Binaya Regmi, MD · RWTH Aachen University

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2024-12-01
Completion
2024-12-01

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06105450 on ClinicalTrials.gov