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Respiratory Muscle Strength and Function in Neuromuscular Disorders and Chronic Obstructive Pulmonary Disease

NCT03032562 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2017-01-26

No results posted yet for this study

Summary

Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to

* identify disease-specific patterns of respiratory muscle impairment in different NMD and COPD
* establish which set of tests is predictive of sleep-disordered breathing or daytime hypercapnia in patients with NMD or COPD, respectively.
* to investigate the decline of respiratory muscle function in patients with progressive NMD and COPD along with sleep studies and capnography

Conditions

  • Respiratory Muscle Paralysis

Interventions

DIAGNOSTIC_TEST

Multimodal measurement of respiratory muscle function and strength

Sleep-studies, capnography, spiromanometry, phrenic nerve conduction studies, magnetic phrenic nerve stimulation, diaphragmatic ultrasound

Sponsors & Collaborators

  • Universität Münster

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-01
Primary Completion
2019-12-31
Completion
2020-02-28

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03032562 on ClinicalTrials.gov