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Predictors of HFNC Failure in Patients With AHRF Using Echocardiography Parameters

NCT06096363 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2024-10-16

No results posted yet for this study

Summary

Right ventricular dysfunction (RVD) and right ventricular-pulmonary arterial (RV-PA) uncoupling detected by transthoracic echocardiography (TTE) in acute respiratory distress syndrome (ARDS) are associated with poor survival. Early detection of RVD and RV-PA uncoupling in patients with acute hypoxemic respiratory failure (AHRF) may be indicative of worsening and decompensating pulmonary condition which may require escalation of respiratory support. The use of TTE parameters in predicting high-flow nasal cannula (HFNC) failure has not been previously studied. The objective of this study is to identify predictors of HFNC failure by TTE and to compare its performance with the well-established ROX index.

Conditions

  • Acute Hypoxemic Respiratory Failure

Interventions

DIAGNOSTIC_TEST

Transthoracic Echocardiography

Transthoracic Echocardiography to look for evidence of right ventricular (RV) dysfunction and right ventricular-pulmonary arterial (RV-PA) uncoupling.

Sponsors & Collaborators

  • Queen Mary Hospital, Hong Kong

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-28
Primary Completion
2024-06-26
Completion
2024-09-01

Countries

  • Hong Kong

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06096363 on ClinicalTrials.gov