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Targeted Metabolomics and Spent Embryo Culture Medium

NCT06094439 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2023-10-30

No results posted yet for this study

Summary

More than 8 million babies have been born through in vitro fertilization (IVF). Non-invasive observation of embryos in vitro to better understand their development is becoming increasingly important. Morphology has been used as standard from the beginning, but has the disadvantage of subjectivity. Now the emphasis in basic and clinical research is on developing rapid, quantitative, non-invasive tests. Hence comes the idea of metabolic profiling of spent embryo culture medium (SECM) as a biomarker. This could be useful for understanding and improving the nutritional environment of oocytes and embryos. The goal of our study is to determine metabolic profiles of the SECM in combination with morphological assessments to better understand the nutritional requirements of the embryo. The goal would be to optimize media specifically, depending on patient and embryo characteristics ("personalized medicine") ("the embryo in vitro as patient").

Conditions

  • Embryo Culture Media
  • Metabolomics

Sponsors & Collaborators

  • gyn-medicum Göttingen

    lead OTHER

Principal Investigators

  • Andreas Schmutzler, PD Dr. med. · gyn-medicum Göttingen

Eligibility

Min Age
35 Years
Max Age
46 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2024-12-30
Completion
2025-12-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06094439 on ClinicalTrials.gov