Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment
NCT06090682 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2023-10-19
Summary
This study intends to apply structural and functional brain network neuroimaging techniques combined with image post-processing methods to explore the differences in brain network changes in PD patients with cognitive impairment after DBS or TMS.
Conditions
- Parkinson Disease
- Cognitive Impairment
Interventions
- DEVICE
-
Deep Brain Stimulation(DBS) and Transcranial Magnetic Stimulation(TMS)
We observed the changes in cognitive function of patients before and after different brain stimulation treatments, and further compared the effects of different brain stimulation treatments on cognitive function of PD patients and the related mechanisms according to whether DBS surgery was performed or TMS therapy was given only according to the surgical indications.
Sponsors & Collaborators
-
Tianjin Huanhu Hospital
lead OTHER
Eligibility
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-01
- Primary Completion
- 2026-11-01
- Completion
- 2027-11-01
Countries
- China
Study Locations
More Related Trials
-
Concurrent Transcranial Direct Current Stimulation and Gait Training in Parkinson's Disease
NCT04041661 ·Status: UNKNOWN ·Phase: NA
-
Neuropsychiatric Effects of Deep Brain Stimulation in Patients With Parkinson's Disease
NCT01306539 ·Status: COMPLETED ·Phase: NA
-
The Effect of Dual-site Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
NCT05925296 ·Status: UNKNOWN ·Phase: NA
-
Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease
NCT07022522 ·Status: RECRUITING ·Phase: NA
-
Transcranial Magnetic Stimulation in Parkinson's Disease
NCT00023062 ·Status: COMPLETED
-
The Efficacy and Mechanism of SMA+M1 Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
NCT06415682 ·Status: COMPLETED ·Phase: NA
-
Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients
NCT02599753 ·Status: COMPLETED ·Phase: PHASE2
-
Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease
NCT06518824 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Deep-coil Based Repetitive Transcranial Magnetic Stimulation in the Treatment of Parkinson's Disease With Freezing of Gait and Its Neural Regulation Mechanism Study of Resting-state Cerebral Blood Flow
NCT06888778 ·Status: COMPLETED ·Phase: NA
-
tDCS on Parkinson's Disease Cognition
NCT03025334 ·Status: RECRUITING ·Phase: NA
-
Transcranial Direct Current Stimulation and Dual Tasks
NCT05871359 ·Status: RECRUITING ·Phase: NA
-
Individual Neuromodulation for PDS
NCT06193278 ·Status: UNKNOWN ·Phase: NA
-
Deep Brain Stimulation on Dual-task Gait Performance in PD
NCT05314322 ·Status: UNKNOWN ·Phase: NA
-
Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson's Patients
NCT00179101 ·Status: COMPLETED
-
An Open-label Study on the Clinical Efficacy of tDCS Intervention in PD
NCT06566313 ·Status: COMPLETED ·Phase: NA
-
Investigation of the Benefits of Electrical Non-invasive Stimulation on Cognitive Symptoms in Parkinson's Disease
NCT05808504 ·Status: RECRUITING ·Phase: NA
-
Home-based Transcranial Static Magnetic Field Stimulation (tSMS) of the Supplementary Motor Area in Parkinson's Disease
NCT06840678 ·Status: RECRUITING ·Phase: PHASE1
-
Dual-target, High-dose TMS for PD Patients With FOG
NCT05625386 ·Status: TERMINATED ·Phase: NA
-
Motor Skill Learning in People With Parkinson's Disease
NCT00396942 ·Status: COMPLETED
-
Curative Effect and Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Sleep Disorders of PD
NCT05806736 ·Status: COMPLETED ·Phase: NA
-
Neural Correlates of Cognition in Parkinson's Disease
NCT02975193 ·Status: COMPLETED ·Phase: NA
-
Use of Noninvasive Brain Stimulation in Parkinson's Disease
NCT01113086 ·Status: COMPLETED ·Phase: NA
-
Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms
NCT06409338 ·Status: RECRUITING ·Phase: NA
-
Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease
NCT05400499 ·Status: RECRUITING
-
Internet-CBT for Parkinsons Disease
NCT02627885 ·Status: COMPLETED ·Phase: NA