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Neural Correlates of Cognition in Parkinson's Disease

NCT02975193 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2021-02-15

No results posted yet for this study

Summary

Cognitive impairment in Parkinson's disease (PD) has far-reaching effects on both motor outcomes and quality of life in PD patients. Furthermore, deep brain stimulation (DBS), now an evidence-based treatment for certain cases of PD, has the risk of causing deficits in multiple areas of cognition.

As such, the purpose of this study is to understand the neuroanatomical and neurophysiologic basis for impaired cognition in PD. The aim is to identify neural correlates of cognition by measuring brain signal activity while PD patients are engaged in cognition on a computer.

Conditions

  • Parkinson Disease

Interventions

BEHAVIORAL

Computer task assessing cognition

Participants will complete a short computer game to assess cognition.

BEHAVIORAL

Impulsive-Compulsive Disorders in Parkinson's Disease

Standard clinical questionnaire

PROCEDURE

Deep Brain Stimulation Surgery

DBS surgery for the implantation of electrodes for the treatment of motor disorders.

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH

  • University of Florida

    lead OTHER

Principal Investigators

  • Aysegul Gunduz, PhD · University of Florida

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2020-10-25
Completion
2020-10-25

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02975193 on ClinicalTrials.gov