Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures
NCT06084689 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2025-09-02
Summary
Phase II, multicenter, open-label, multi-cohort proof-of-concept study designed to evaluate the safety and efficacy of Ezabenlimab combined with BI 907828 in patients with unresectable, locally advanced or metastatic solid tumors.
Conditions
- Adult Soft Tissue Sarcoma
- Non Small Cell Lung Cancer
- Triple Negative Breast Cancer
- Colorectal Cancer
- Biliary Tract Cancer
Interventions
- DRUG
-
Ezabenlimab + BI907828
A treatment cycle consists of 3 weeks. Both treatments will be administered on Day 1 of each cycle.
Sponsors & Collaborators
- collaborator INDUSTRY
-
Institut Bergonié
lead OTHER
Principal Investigators
-
Antoine ITALIANO, MD, PhD · Institut Bergonié
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-06-14
- Primary Completion
- 2024-07-01
- Completion
- 2024-07-01
Countries
- France
Study Locations
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