Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Summary

In this study, the investigators will prospectively recruit 100,000 individuals, including gastric cancer patients who have not undergone any anti-tumor treatment and non-gastric cancer participants. The investigators will construct a diagnostic model for malignant tumors based on the combination of tongue imaging, tongue coating, saliva, gastric juice, and fecal multi-omics data (including metagenomics, proteomics, metabolomics, etc.). Additionally, the study will explore the relationship between oral, gastric, and intestinal microbiota and the development of malignant tumors.

Conditions

• Gastric Cancer
• Tongue Images
• Diagnosis

Interventions

DIAGNOSTIC_TEST

Tongue imaging, tougue coating, saliva, gastric juice, and feces

Tongue images, coating, saliva, gastric juice, and feces on the tongue and clinical data of patients with gastric cancer and healthy participants will be collected.

Sponsors & Collaborators

• Sichuan Cancer Hospital and Research Institute

  collaborator OTHER

• The First Affiliated Hospital of Zhejiang Chinese Medical University

  collaborator OTHER

• Wenzhou Medical University

  collaborator OTHER

• Fujian Cancer Hospital

  collaborator OTHER_GOV

• RenJi Hospital

  collaborator OTHER

• Tongde Hospital of Zhejiang

  collaborator UNKNOWN

• Kecheng District People's Hospital

  collaborator UNKNOWN

• Yueyang Central Hospital

  collaborator OTHER

• Shandong Cancer Hospital and Institute

  collaborator OTHER

• Shanxi Province Cancer Hospital

  collaborator OTHER

• Liaoning Cancer Hospital & Institute

  collaborator OTHER

• Harbin Cancer Hospital

  collaborator UNKNOWN

• Yuhang District People's Hospital

  collaborator UNKNOWN

• Hainan Cancer Hospital

  collaborator OTHER

• Zigong Fourth People's Hospital

  collaborator UNKNOWN

• Henan University of Science and Technology

  collaborator OTHER

• Shangyu People's Hospital of Shaoxing City

  collaborator UNKNOWN

• Red Cross Hospital, Hangzhou, China

  collaborator OTHER

• The Affiliated Hospital of Hangzhou Normal University

  collaborator OTHER

• Xiaoshan District First People's Hospital

  collaborator UNKNOWN

• Xianju County People's Hospital

  collaborator UNKNOWN

• Lin'an District First People's Hospital

  collaborator UNKNOWN

• First Affiliated Hospital of Wenzhou Medical University

  collaborator OTHER

• Wenzhou Central Hospital

  collaborator OTHER

• The Third Affiliated Hospital of Wenzhou Medical University

  collaborator OTHER

• Leqing City People's Hospital

  collaborator UNKNOWN

• The Affiliated Hospital of Medical School of Ningbo University

  collaborator UNKNOWN

• Cixi City People's Hospital

  collaborator UNKNOWN

• Mingzhou Hospital, Zhejiang University

  collaborator UNKNOWN

• Fourth Hospital of Ningbo City

  collaborator UNKNOWN

• Fenghua District People's Hospital

  collaborator UNKNOWN

• Fenghua Traditional Chinese Medicine Hospital, Ningbo City

  collaborator UNKNOWN

• Xikou Hospital, Fenghua District, Ningbo City

  collaborator UNKNOWN

• Chengdu University of Traditional Chinese Medicine

  collaborator OTHER

• Guang'an Hospital, Affiliated to Chengdu University of Traditional Chinese Medicine

  collaborator UNKNOWN

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• Jiangsu Provincial People's Hospital

  collaborator OTHER

• The First People's Hospital of Changzhou

  collaborator OTHER

• The First Affiliated Hospital of Soochow University

  collaborator OTHER

• Jiangsu Provincial Hospital of Traditional Chinese Medicine

  collaborator UNKNOWN

• Zidong Campus of Jiangsu Provincial Hospital of TCM

  collaborator UNKNOWN

• Wuxi Traditional Chinese Medicine Hospital

  collaborator UNKNOWN

• First Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• The First Affiliated Hospital of Anhui Medical University

  collaborator OTHER

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Xijing Hospital

  collaborator OTHER

• Guangdong Provincial Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Xiangya Hospital of Central South University

  collaborator OTHER

• Yunnan Cancer Hospital

  collaborator OTHER

• Chongqing University Cancer Hospital

  collaborator OTHER

• Gansu Cancer Hospital

  collaborator OTHER

• Fudan University

  collaborator OTHER

• Cancer Institute and Hospital, Chinese Academy of Medical Sciences

  collaborator OTHER

• First Affiliated Hospital of Guangxi Medical University

  collaborator OTHER

• Tianjin Medical University Cancer Institute and Hospital

  collaborator OTHER

• Huzhou Central Hospital

  collaborator OTHER

• Zhoushan Hospital, Zhejiang

  collaborator UNKNOWN

• Zhejiang Cancer Hospital

  lead OTHER

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-06-01

Primary Completion

2025-06-01

Completion

2026-12-31

Countries

• China

Study Locations