Evaluation of a Couple-Based Physical Activity Intervention

Summary

This clinical trial tests how well a couple-based physical activity (PA) intervention, Mates in Motion, works in patients undergoing hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell therapy (CART) and their care giving partners to be more physically active. Mates in Motion provides training in communication skills and behavior change techniques to help HCT patient-caregiver dyads support one another in adoption and maintenance of PA. This study may help researchers determine if a couple-based PA intervention improves PA, physical endurance and global physical health among patient-care giver dyads undergoing HCT or CART.

Conditions

• Hematopoietic and Lymphoid System Neoplasm
• Malignant Solid Neoplasm

Interventions

OTHER

Best Practice

Receive usual care

OTHER

Exercise Counseling

Receive walking step goals

OTHER

Exercise Intervention

Participate in Mates in Motion program

OTHER

Medical Device Usage and Evaluation

Wear Actigraph

OTHER

Medical Device Usage and Evaluation

Wear Garmin activity tracker

OTHER

Physical Performance Testing

Undergo walk-test

OTHER

Questionnaire Administration

Complete questionnaires

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• Mayo Clinic

  lead OTHER

Principal Investigators

• Nandita Khera, MD, MPH · Mayo Clinic

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-03-11

Primary Completion

2025-09-03

Completion

2025-09-03

Countries

• United States

Study Locations