MedTrace Logo

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV

NCT06045923 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-05-05

No results posted yet for this study

Summary

The purpose of this study is to examine the extent of mpox viral spread and immunologic markers in people with advanced HIV. Study findings will enhance knowledge of mpox pathogenesis in severely immunocompromised people, which can inform treatment and prevention of severe illness and deaths associated with mpox in people with advanced HIV.

Conditions

  • Monkeypox
  • HIV Infections
  • AIDS

Sponsors & Collaborators

Principal Investigators

  • Agam Rao, MD · Centers for Disease Control and Prevention

  • Irini Sereti, MD · National Institutes of Health (NIH)

  • Faisal Minhaj, Pharm.D. · Centers for Disease Control and Prevention

  • Shama Cash-Goldwasser, MD · Centers for Disease Control and Prevention

  • Jesse OShea, MD · Centers for Disease Control and Prevention

  • Christine Hughes, PhD · Centers for Disease Control and Prevention

  • Brian Epling, MD · National Institutes of Health (NIH)

  • Katy Saliba, PhD · National Institutes of Health (NIH)

  • Jason Zucker, MD · Columbia University

  • Sarah Reagan Steiner, MD · Centers for Disease Control and Prevention

  • Sarah Park, MD · Karius Laboratories

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-17
Primary Completion
2026-01-01
Completion
2026-01-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06045923 on ClinicalTrials.gov