Diastolic Function in Myotonic Dystrophy Type 1
NCT06029192 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2023-09-08
Summary
Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder in relation with an unstable expansion of CTG repeat. Patients with DM1 are at risk of arrhythmia and conduction disorders. Mortality are mainly related to respiratory failure and sudden death. Patients with DM1 may suffer from obesity, arterial hypertension, diabetes mellitus and sleep apnea. These comorbidities are classically associated with left ventricular diastolic dysfunction (DD) .
The investigators aim to assess the prevalence of left ventricular diastolic dysfunction in patients with myotonic dystrophy type 1 , the distribution of DD grading as well as the long-term prognosis of DM1 patients with a left ventricular diastolic dysfunction.
Conditions
- Diastolic Dysfunction
Sponsors & Collaborators
-
Centre d'Investigation Clinique et Technologique 805
lead OTHER
Principal Investigators
-
Abdallah FAYSSOIL, MD PhD · CHU Raymond Poincare
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-06-02
- Primary Completion
- 2023-10-02
- Completion
- 2023-11-01
Countries
- France
Study Locations
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