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Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis

NCT06025903 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2024-03-22

No results posted yet for this study

Summary

The purpose of this project is to study genetic determinants of mitochondrial impairment in primary progressive multiple sclerosis. Specific aims are: 1) identify mitochondrial-related pathways, inherited and somatic mitochondrial DNA mutations associated to primary progressive multiple sclerosis, 2) functionally assess the identified genetic alterations.

Conditions

Sponsors & Collaborators

  • Azienda Socio Sanitaria Territoriale della Valle Olona

    collaborator OTHER

  • IRCCS San Raffaele

    lead OTHER

Principal Investigators

  • Melissa Sorosina · IRCCS San Raffaele

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-20
Primary Completion
2024-09-30
Completion
2025-05-30

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06025903 on ClinicalTrials.gov