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Feasibility of Improving Glycemia With Heat Therapy to Prevent AD

NCT06023407 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-04-17

No results posted yet for this study

Summary

The investigators will determine if heat therapy can improve blood (Aim 1) and brain (Aim 2) glucose metabolism in cognitively healthy older adults (65+) who are at risk for AD. The investigators will also examine the degree to which changes in blood and brain glucose metabolism track together and explore several additional potential mechanisms that are critical to understanding the brain benefits of heat therapy (Aim 3). These aims will provide a comprehensive understanding of the impact of heat therapy on whole body metabolic function and brain health.

Conditions

  • Healthy Aging
  • Alzheimer Disease
  • Metabolic Disease

Interventions

OTHER

Water Immersion Heat Therapy

10-weeks of 3 days per week in 1 of the 2 arms

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • University of Kansas Medical Center

    lead OTHER

Principal Investigators

  • Jill Morris · University of Kansas Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-27
Primary Completion
2027-10-29
Completion
2028-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06023407 on ClinicalTrials.gov