Nimotuzumab for EGFR-amplified Advanced Pan Solid Tumors
NCT06022276 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46
Last updated 2023-09-01
Summary
To evaluate the efficacy and safety of nimotuzumab in the treatment of EGFR-amplified advanced pan solid tumors (Lung/Esophageal/Gastric/Pancreatic /Colorectal / Head and neck Cervical).
Conditions
- Solid Tumor
- EGFR Amplification
Interventions
- DRUG
-
Nimotuzumab
Nitozumab injection 400mg/cycle, every 21 days/cycle, until disease progression, intolerable toxicity or death, or subject decision to withdraw from the study.The molecular testing results of the patient are analyzed and interpreted by the MTB team, and appropriate combination therapy(Nitozumab+) strategies are proposed based on the patient's previous treatment history, physical condition, drug accessibility, and economic status.
Sponsors & Collaborators
-
Tianjin Medical University Second Hospital
lead OTHER
Principal Investigators
-
HaiTao Wang, Ph.D · Tianjin Medical University Second Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-12-01
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- China
Study Locations
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