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Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study

NCT06017141 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2023-08-30

No results posted yet for this study

Summary

This trial evaluates how inhalational anesthesia (drawn in through the lungs) and total intravenous anesthesia (TIVA) (through a needle in a vein in the arm) change the body's ability to recover from surgery or whether they impact the immune system immediately after surgery in patients with colon cancer. It is unknown whether these types of anesthesia change recovery from surgery or change the chances cancer comes back following surgery. This study may help researchers learn how different types of anesthesia affect recovery from colon cancer surgery.

Conditions

  • Colon Adenocarcinoma

Interventions

PROCEDURE

Biospecimen Collection

Undergo blood and tissue sample collection

OTHER

Electronic Health Record Review

Ancillary studies

DRUG

Fentanyl Citrate

Given via injection

DRUG

Propofol

Given IV

OTHER

Questionnaire Administration

Ancillary studies

DRUG

Sevoflurane

Given via inhalation

PROCEDURE

Surgical Procedure

Undergo SOC surgery

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • University of Kansas Medical Center

    lead OTHER

Principal Investigators

  • Luke V Selby · University of Kansas

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-22
Primary Completion
2025-05-22
Completion
2026-05-22

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06017141 on ClinicalTrials.gov