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the Study of Effect of Chronomodulated Chemotherapy on the Dendritic Cells Subsets in the Treatment of Advanced Nasopharyngeal Cancer

NCT03196869 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 128

Last updated 2017-06-23

No results posted yet for this study

Summary

This study is to observe and compare the effect of docetaxel plus lobaplatin induction chemotherapy combined with lopoplatin chemoradiotherapy and TPF induction chemotherapy combined with cisplatin chemoradiotherapy on dendritic cells subsets in the treatment of locally advanced head and neck squamous cell carcinoma.

Conditions

  • Locally Advanced Head and Neck Squamous Cell Carcinoma

Interventions

DEVICE

Chrono-chemotherapy

Chrono-chemotherapy+concurrent radiochemotherapy

DEVICE

Routine intravenous drip

Routine intravenous drip-chemotherap

DRUG

induction Chrono-chemotherapy

Experimental group:docetaxel,cisplatin,5-FU

DRUG

induction Routine-chemotherapy

control group:docetaxel,cisplatin,5-FU

DRUG

cisplatin chrono-chemotherapy

Experimental group: cisplatin chrono-chemotherapy

DRUG

cisplatin routine-chemotherapy

control group:cisplatin routine-chemotherapy

RADIATION

intensity-modulated radiation therapy

control group is similar to Experimental group

Sponsors & Collaborators

  • Guiyang Medical University

    lead OTHER

Principal Investigators

  • Feng Jin, Bachelor · Guizhou Provincial Cancer Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-04-07
Primary Completion
2019-04-12
Completion
2022-08-12

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03196869 on ClinicalTrials.gov