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Does Mirabegron Increase the Body Heat Generated by the Nervous System

NCT06011265 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2024-06-06

No results posted yet for this study

Summary

Acute mirabegron administration has been shown to increase brown fat activity in humans. Long-term mirabegron administration upregulates brown fat, and appears to improve glucose regulation, and change skeletal muscle phenotype.

Conditions

  • Thermoregulation

Interventions

DRUG

Myrbetriq 25Mg Extended-Release Tablet

Participants take 4x 25mg Myrbetriq 25Mg Extended-Release Tablet orally.

DRUG

Placebo

Participants take empty capsule orally

Sponsors & Collaborators

  • Indiana University

    collaborator OTHER

  • Christopher Bell

    lead OTHER

Principal Investigators

  • Christopher Bell, Ph.D. · Colorado State University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-27
Primary Completion
2024-01-17
Completion
2024-04-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06011265 on ClinicalTrials.gov