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Phototherapy: Not a Cause of Demodicosis

NCT06000189 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2023-08-21

No results posted yet for this study

Summary

The purpose of this study is to determine whether there is an increase in the frequency of demodicosis and the density of Demodex mites after 20 sessions of phototherapy.

The main question(s)it aims to answer are;

* Are Demodex mites higher in patients treated with phototherapy?
* In which localization and with what intensity was demodicosis most common? Participants will be assessed using standardized skin surface biopsy technique in four localization on their face.

Researchers will compare demodex intensity per cm² to see if the phototherapy effects demodex intensity on patients.

Conditions

  • Demodicidosis

Interventions

PROCEDURE

Standardized skin surface biopsies (SSSB)

Skin samples will be obtained from four regions of the participants' faces, including the forehead, right cheek, left cheek, and the nose, before phototherapy and after 20 sessions of phototherapy. The SSSB will be performed as follows: a 1 cm² square will be drawn on a glass slide using a ruler. The skin areas to be sampled will be gently swabbed with a dry gauze to induce irritation by this way to obtain more mites. Then, one drop of cyanoacrylate adhesive will be dropped onto the marked area on the glass slide, and the adhesive surface of the slide will be pressed onto the skin surface for approximately one minute. Afterwards, the slide will be gently lifted, and the sampled area will be examined under a light microscope at x10 and x40 magnifications after applying immersion oil. The presence of more than five Demodex mites per square centimeter will be defined as increased Demodex density.

Sponsors & Collaborators

  • Istanbul Medeniyet University

    lead OTHER

Principal Investigators

  • Melek Aslan Kayıran, Ass.Prof · Istanbul Medeniyet University

  • sümeyye Altıntaş Kakşi, Specialist · Istanbul Medeniyet University

  • Vefa Aslı Erdemir, Prof · Istanbul Medeniyet University

  • Yeşim Dede, Resident · Istanbul Medeniyet University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2023-08-30
Completion
2023-08-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06000189 on ClinicalTrials.gov