NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
NCT05992883 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 240
Last updated 2026-02-23
Summary
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).
Conditions
- Thumb Osteoarthritis
Interventions
- DRUG
-
Ketorolac
Intervention will be an injection containing 1.0 mL of ketorolac 15 mg/mL (15 mg total of ketorolac).
- DRUG
-
Triamcinolone
Intervention will be an injection containing 0.5 mL of triamcinolone 40 mg/mL (20 mg total of triamcinolone).
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Marco Rizzo, MD · Mayo Clinic
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-28
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Efficacy of Intra-articular NSAID Versus Corticosteroid in the Treatment of Shoulder and Knee Conditions: A Randomized, Double-Blind, Prospective Study
NCT03616340 ·Status: UNKNOWN ·Phase: PHASE3
-
Corticosteroid Intra-articular Injection in Hands Osteoarthritis
NCT02102620 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb
NCT00398866 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
NCT06237153 ·Status: RECRUITING ·Phase: PHASE2
-
Knee Injection RCT
NCT03694821 ·Status: TERMINATED ·Phase: PHASE4
-
Intraarticular Injections of the Hip and Knee With Triamcinolone Versus Ketorolac: A Randomized Controlled Trial
NCT04441112 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Triamcinolone Ketorolac (TriKe) Knee Trial
NCT05336968 ·Status: RECRUITING ·Phase: PHASE4
-
Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb
NCT04829565 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
NCT02536833 ·Status: COMPLETED ·Phase: PHASE2
-
Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial
NCT02995083 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis
NCT02576249 ·Status: COMPLETED ·Phase: PHASE4
-
Knee Injections for Obese Patients With Knee Arthritis
NCT06782529 ·Status: RECRUITING ·Phase: PHASE4
-
Is Botox Effective in Relieving Pain From Knee Osteoarthritis?
NCT00279903 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment
NCT06657300 ·Status: COMPLETED ·Phase: PHASE4
-
A Trial to Assess the Pain-control Efficacy of Intra-articular Toradol Compared to Oral NSAIDs
NCT02966288 ·Status: WITHDRAWN ·Phase: PHASE4
-
The Comparative Study of Intra-articular Injection of Tocilizumab and Compound Betamethasone
NCT03215407 ·Status: UNKNOWN ·Phase: PHASE4
-
Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial
NCT04115644 ·Status: TERMINATED ·Phase: PHASE4
-
Using Ultrasound to Predict Response to Intraarticular Corticosteroids in Knee Osteoarthritis
NCT00746889 ·Status: COMPLETED ·Phase: NA
-
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
NCT06193499 ·Status: RECRUITING ·Phase: NA
-
Corticosteroid vs Platelet-Rich Plasma Intra-articular Injections in the Treatment of Knee Osteoarthritis.
NCT06032039 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base
NCT04218591 ·Status: COMPLETED ·Phase: NA
-
Study of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the Knee
NCT01887678 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Different Injection Regimens of Autologous Conditioned Plasma for Knee Osteoarthritis
NCT03889925 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Comparing Intra-articular Corticosteroid to Intra-articular Ketorolac Knee Injections
NCT02612272 ·Status: UNKNOWN ·Phase: PHASE4
-
Genicular Nerve Block in Rheuamtoid Arthritis
NCT04361513 ·Status: COMPLETED ·Phase: PHASE4