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Role of Adrenaline in in the Inflammatory Response in Diabetes

NCT05990933 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-11-21

No results posted yet for this study

Summary

The primary aim of the present study is to study the effect of adrenaline administration on inflammatory parameters (e.g. leukocyte phenotype, cytokines, inflammatory proteins). Secondary objectives consist of the effect of adrenaline on atherogenic parameters.

* All participants will receive intravenous infusion of adrenaline for an hour
* We will draw blood at 7 time points, not including screening
* Participants will be asked to return for a total of 4 times

Researchers will compare 2 groups, healthy individuals versus people with diabetes type 1 to see if the inflammatory reaction to adrenaline differs between these two groups.

Conditions

Interventions

DRUG

Adrenaline

Adrenaline infusion at a rate of 0.04ug/kg/min for 1 hour administered intravenously.

Sponsors & Collaborators

  • Cees Tack

    lead OTHER

Principal Investigators

  • Cees Tack, MD. PHD. · Radboud University Medical Center (Radboudumc)

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
16 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-12-03
Primary Completion
2024-09-03
Completion
2024-09-03

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05990933 on ClinicalTrials.gov