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Counterregulatory Hormone Production in Adrenal Insufficiency and Diabetes Type I

NCT01452893 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2014-01-06

No results posted yet for this study

Summary

Patients with adrenal insufficiency also exhibit an adrenomedullary dysfunction. Furthermore, patients who suffer from both, adrenal insufficiency and type I diabetes more frequently report hypoglycemia, particularly after strenuous activities. The study investigates the counter regulatory hormonal response to physical stress and the impact on cognitive function in subjects with and without Addison's disease, type I diabetes and healthy subjects.

Conditions

Interventions

PROCEDURE

Spiroergometry

At visit 1 determination of the individual VO2max (maximal oxygen uptake) by spiroergometry after first testing of cognitive function. At visit 2: Spiroergometry with 3 min warm up followed by 5 min 50% VO2max and 15 min at the individual respiratory compensation point (RCP).

Sponsors & Collaborators

  • University of Wuerzburg

    lead OTHER

Principal Investigators

  • Bruno Allolio, MD · University of Wuerzburg

  • Stefanie Hahner, MD · University of Wuerzburg

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2012-05-31
Completion
2013-12-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01452893 on ClinicalTrials.gov