Steroid for Treatment of Acute/Subacute Severe Cerebral Venous Thrombosis.
NCT05990894 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 170
Last updated 2025-07-11
Summary
The cohort study aims to evaluate the efficacy and safety of steroids combined with anticoagulant therapy compared to standard anticoagulant therapy in acute/subacute severe cerebral venous thrombosis.
Conditions
- Cerebral Venous Thrombosis
Interventions
- DRUG
-
Methylprednisolone
In the steroid therapy group, patients received standard treatment plus steroid therapy. Steroid therapy protocol is as follows: 500 mg methylprednisolone once a day, intravenous drip for 3 days, then reduced to 80 mg once a day, intravenous drip for 5 days, and changed to oral methylprednisolone/prednisone 1 mg per kilogram body weight, gradually tapered off by a dose of 10 mg per week.
Sponsors & Collaborators
-
Xuanwu Hospital, Beijing
lead OTHER
Principal Investigators
-
Jiangang Duan, MD, PhD · Xuanwu Hospital, Beijing
Eligibility
- Min Age
- 14 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-07-01
- Primary Completion
- 2024-07-31
- Completion
- 2024-07-31
- FDA Drug
- Yes
Countries
- China
Study Locations
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