Functional Cure of Hepatitis B in HIV/HBV Co-infected Patients
NCT05988879 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2023-08-14
Summary
Evaluate the potential of ART combined with interferon therapy to achieve functional cure of hepatitis B in HIV/HBV co-infected patients
Conditions
- AIDS
- Hepatitis B
Interventions
- DRUG
-
Peginterferon alfa-2b Injection
The pegylated interferon α-2b injection is administered subcutaneously at a dose of 180ug once a week.
Sponsors & Collaborators
-
Guangzhou 8th People's Hospital
lead OTHER
Principal Investigators
-
Linghua Li, PhD · Guangzhou Eighth People's Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-02
- Primary Completion
- 2026-08-02
- Completion
- 2028-08-02
Countries
- China
Study Locations
More Related Trials
-
A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B
NCT04846491 ·Status: COMPLETED ·Phase: PHASE3
-
Study on the Treatment of Hepatitis B Virus(HBV) Infected Individuals With Peginterferon α-2b Combined With NA.
NCT06746701 ·Status: RECRUITING
-
Combination or Sequential Therapy of Peginterferon Alfa-2a and Entecavir for Patients With Chronic Hepatitis B
NCT01906580 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Peginterferon Consolidation Therapy on Hepatic cccDNA Dynamics in CHB Patients Achieving Clinical Cure.
NCT06920329 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Optimized Treatment of Peginterferon Alfa 2a/2b in Treatment Experienced Patients With HBV Related Liver Fibrosis
NCT03920605 ·Status: UNKNOWN ·Phase: NA
-
Combination Treatment of NAs and Peg IFN α-2b for Hepatitis B Related, Compensatory Cirrhosis Patients
NCT03969017 ·Status: UNKNOWN ·Phase: PHASE2
-
Optimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver Fibrosis
NCT03957629 ·Status: UNKNOWN ·Phase: NA
-
A Follow-up Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B
NCT06707922 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients
NCT05182463 ·Status: RECRUITING ·Phase: PHASE4
-
Optimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With HBV Related Liver Fibrosis
NCT03919565 ·Status: UNKNOWN ·Phase: NA
-
To Optimize the Therapeutic Pathway of Peginterferon Treatment in Patients With CHB Based on IFNA2p.Ala120Thr /ISGs.
NCT03771677 ·Status: UNKNOWN ·Phase: NA
-
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)
NCT05771402 ·Status: RECRUITING ·Phase: PHASE2
-
Prospective Cohort Study on PEG-IFN-α-2b in Improving Clinical Cure Rate of Pediatric Patients With Chronic Hepatitis B
NCT07231276 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
HBsAg Loss/Seroconversion in Low Replicative Chronic Hepatitis B Virus(HBV) Infection Patients
NCT02908763 ·Status: UNKNOWN ·Phase: PHASE4
-
Hepatitis B Virus Mutants and the Therapeutic Effect of Peginterferon Alfa-2a in HBeAg-Positive Chronic Hepatitis B
NCT01311947 ·Status: COMPLETED
-
The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg
NCT02745704 ·Status: UNKNOWN ·Phase: PHASE4
-
HBsAg Clearance in Inactive Chronic HBsAg Carriers After Interferon Treated
NCT01471535 ·Status: COMPLETED ·Phase: NA
-
A Study on Peginterferon Alfa-2b Combined With NAs in Compensated HBV Cirrhosis
NCT07183293 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study to Evaluate Addition of Peginterferon Alfa-2a to Chronic Hepatitis B (CHB) Patients Treated With NAs
NCT02894918 ·Status: UNKNOWN ·Phase: PHASE4
-
Pegylated Interferon α in Previously Interferon-treated CHB(Leading Study)
NCT06323681 ·Status: RECRUITING ·Phase: NA
-
Efficacy and Safety of Peginterferon a-2a in Patients of Chronic Hepatitis B With Spontaneous Decline of HBV DNA
NCT01892241 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Extended Peginterferon Alpha 2a Treatment in HBeAg Positive Chronic Hepatitis B Patients
NCT02387463 ·Status: COMPLETED
-
Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Hepatitis B Patient
NCT03294798 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Changes of Natural Killer Cells Frequency and Function During Antiviral Therapy
NCT03208998 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficay of Extended Peginterferon Alpha 2a Treatment in HBeAg Negative Chronic Hepatitis B Patients
NCT02387684 ·Status: UNKNOWN