MedTrace Logo

Effect of Quercetin Supplementation on Endometriosis Outcomes

NCT05983224 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2023-08-16

No results posted yet for this study

Summary

Quercetin is a polyphenol compound that possesses anti-inflammatory properties and can be found in various food sources like apples, berries, cabbage, and onions. In Park et al.'s study, it was discovered that quercetin led to a significant decrease in the proliferation of endometriosis cells. Furthermore, quercetin also triggered apoptosis in endometriosis cells in vitro and reduced the size of endometriosis lesions in vivo. Nevertheless, as of now, there have been no studies conducted in Iran or worldwide that explore the effects of quercetin supplementation on individuals with endometriosis. Hence, the aim of this study is to investigate the impact of quercetin supplementation on factors such as glycemic status, lipid profile, oxidative stress, inflammation, growth factors, adiponectin, sex hormones, and anthropometric indicators in women suffering from endometriosis.

Conditions

  • Endometriosis

Interventions

DIETARY_SUPPLEMENT

Quercetin

The intervention group will receive two 500 mg quercetin tablets daily, after breakfast and lunch, for twelve weeks.

OTHER

Placebo

The control group will receive two placebo daily, after breakfast and lunch, for twelve weeks.

Sponsors & Collaborators

  • Shahid Beheshti University of Medical Sciences

    collaborator OTHER

  • National Nutrition and Food Technology Institute

    lead OTHER

Principal Investigators

  • Ghazaleh Eslamian, PhD · National Nutrition and Food Technology Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-15
Primary Completion
2024-01-01
Completion
2024-03-01

Countries

  • Iran

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05983224 on ClinicalTrials.gov