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Endometrial Tissues and Mononuclear Cells Receptivity in Pathogenesis of Endometrial Proliferative Processes

NCT06115577 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 92

Last updated 2023-11-15

No results posted yet for this study

Summary

A prospective observational study of endometrial tissue and peripheral blood mononuclear cells receptivity to sex steroid hormones in postmenopausal patients with endometrial proliferative processes

Conditions

  • Endometrial Hyperplasia Without Atypia
  • Endometrial Hyperplasia With Atypia
  • Endometrial Cancer
  • Peripheral Blood Mononuclear Cells
  • Postmenopause
  • Estrogen Receptor
  • Progesterone Receptor

Interventions

DIAGNOSTIC_TEST

endometrial tissue and peripheral blood mononuclear cells receptivity

Participants investigated the expression level of estrogen and progesterone receptors (ERα, ERβ, GPER, PRA, PRB, mPR, PGRmC1) by RT-PCR in pathological endometrial tissue and peripheral blood mononuclear cells. GABDH was used as a comparison gene.

Sponsors & Collaborators

  • Pirogov Russian National Research Medical University

    lead OTHER

Principal Investigators

  • Dina Gutorova, PhD · Pirogov Russian National Research Medical University

Eligibility

Min Age
53 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-10-01
Primary Completion
2022-08-01
Completion
2022-08-01

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06115577 on ClinicalTrials.gov