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68Ga-FAPI PET/CT to Detect Ongoing Fibroblast Activity in Post-acute COVID-19

NCT05981885 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2024-05-21

No results posted yet for this study

Summary

The goal of this observational study is to investigate the role fibroblasts play in the persistent respiratory complaints after a COVID-19 infection. Fibroblasts are involved in tissue remodeling and repair by creating scar-tissue (fibrosis) after tissue damage has occurred. The hypothesis is that this process of fibrosis is ongoing in patients with persistent complaints. To evaluate the roll of fibroblasts a new type of scan is used that is capable of imaging active fibroblasts, a 68Ga-FAPI PET/CT scan.

Conditions

  • Post-Acute COVID-19
  • Post-Acute COVID-19 Infection
  • Post-Acute COVID-19 Syndrome
  • Pulmonary Fibrosis

Sponsors & Collaborators

  • ZonMw: The Netherlands Organisation for Health Research and Development

    collaborator OTHER

  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • Riemer Slart, Prof MD PhD · University Medical Center Groningen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-09
Primary Completion
2023-11-21
Completion
2024-05-17

Countries

  • Netherlands

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05981885 on ClinicalTrials.gov