[18F]FAPI PET/CT in Suspicious Focal Liver Lesions Without FDG Avidity
NCT05806333 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2023-04-10
Summary
Fibroblast activation protein (FAP) is a serine protease that belongs to the dipeptidyl peptidase-IV (DPP-IV) family located in fbroblast membranes. FAP is overexpressed in the cancer-associated fbroblasts (CAFs) of 90% of epithelial carcinomas, including primary and metastatic liver cancer. We aim to conduct a prospective study to investigate the diagnostic perfoemance of 18F-FAPI PET/CT in evaluating suspicious liver mass without FDG avidity.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
FAPI PET
Drug: 18F-FAPI 18F-FAPI were injected into the patients before the PET/CT scans
Sponsors & Collaborators
-
Jilin University
lead OTHER
Principal Investigators
-
Bin Ji · China-Japan Union Hospital, Jilin University
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-01
- Primary Completion
- 2023-06-01
- Completion
- 2023-06-01
Countries
- China
Study Locations
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