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Epidemiological, Clinical and Biological Caracteristics of Patients Presenting With Invasive Meningococcal Disease

NCT05981599 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-08-09

No results posted yet for this study

Summary

An unusual increase in cases of invasive meningococcal infection between late 2022 and early 2023. These cases sometimes had atypical presentations (large numbers of bacteremias without meningitis). The distribution of serogroups was also unusual in our center (large number of serotype Y meningococcal IMD).

This development comes after three years marked by the Corona-Virus-Disease-19 pandemic, which led to a profound change in the behaviors involved in the transmission of infectious diseases. Barrier measures have considerably reduced the population's exposure to meningococcus, and may have encouraged a reduction in mucosal immunity to this pathogen. The end of 2022 was also marked by intense viral circulation (syncitial respiratory virus-influenza-COVID), which may have favored invasive forms.

Conditions

  • Meningococcal Infections

Interventions

OTHER

There is no intervention

There is no intervention. Only retrieving clinical, biological and epidemiological data from patient files

Sponsors & Collaborators

  • Poitiers University Hospital

    lead OTHER

Principal Investigators

  • France CAZENAVE ROBLOT, PhD · SPILF

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-30
Primary Completion
2023-08-30
Completion
2023-09-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05981599 on ClinicalTrials.gov